Bilateral intracranial electroencephalographic monitoring immediately following corpus callosotomy

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Bilateral intracranial EEG with corpus callosotomy may uncover seizure focus in nonlocalizing focal epilepsy

PURPOSE To evaluate the value of a new multi-stage surgical procedure using bilateral intracranial electroencephalogram (iEEG) prior and post complete corpus callosotomy (CC) for epileptogenic focus localization. METHOD Thirty patients with drug-resistant epilepsy underwent bilateral iEEG monitoring to localize epileptogenic focus for surgical treatment. Among them, bisynchronous epileptogeni...

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Lamotrigine after corpus callosotomy

Corpus callosotomy (CC) has been employed in the management of intractable epilepsy since 1940’ and should be considered for patients with generalized falling seizures with physical injury, recurrent life-threatening generalized convulsive status epilepticus or atypical absence status’. CC is especially useful in improving seizure control in patients with tonic and atonic seizures3 and those wi...

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Reinventing the corpus callosotomy.

Surgical section of the corpus callosum is an old operation. It was first performed to treat epilepsy more than 75 years ago. Early procedures often consisted of a “total commissurotomy,” performed through a right frontoparietal craniotomy, with division of the entire corpus callosum, the ipsilateral fornix, the anterior commissure, and even the massa intermedia of the thalamus. Subsequently, s...

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Corpus callosotomy in refractory idiopathic generalized epilepsy

RATIONALE A small percentage of patients with idiopathic generalized epilepsy (IGE) do not respond to medical therapy. Generalized tonic-clonic (GTC) seizures are especially debilitating and can be associated with severe injuries. The benefit, safety and effect of corpus callosotomy (CC) in patients with IGE have not been studied. METHODS We reviewed patients with presumed IGE who underwent C...

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ژورنال

عنوان ژورنال: Epilepsia

سال: 2010

ISSN: 0013-9580

DOI: 10.1111/j.1528-1167.2010.02568.x